Southampton's 2024/25 Premier League season concludes with a home game against Arsenal, as the Saints look to bounce back from their relegation to the Championship. Mikel Arteta's Arsenal side has secured second place in the league, but will be without several key players, including William Saliba and Jurrien Timber, due to injury. Southampton interim manager Simon Rusk has his own injury concerns, with central defenders Taylor Harwood-Bellis and Jan Bednarek ruled out, and Kyle Walker-Peters a doubt due to illness. The Saints have had a torrid season, earning just 12 points from their 37 games, but will be looking to avoid becoming the worst-ever team in Premier League history. Arsenal, on the other hand, has ended their five-game winless run with a crucial victory over Newcastle United, securing their place in the Champions League next season. The Gunners have a strong record against Southampton, having won their last meeting 3-1 at the Emirates Stadium in October. Cameron Archer had given the Saints the lead, but Arsenal responded swiftly, with Thomas Partey and Declan Rice scoring crucial goals. The two teams will meet again at St Mary's Stadium, with Southampton looking to cause an upset and end their season on a high note. Arsenal's defensive options have been depleted, with Gabriel and Takehiro Tomiyasu also on the treatment table, alongside long-term absentee Gabriel Jesus. The Gunners will be looking to finish their season strongly, but Southampton will be determined to spoil their party. The Saints have managed to avoid being the worst-ever team in Premier League history by a single point, and will be looking to build on that momentum. The game promises to be an exciting encounter, with both teams looking to end their season on a positive note. Southampton's fans will be hoping for a win, but Arsenal's quality and depth may prove too much for the Saints to handle. The match will be a great opportunity for the Saints to test themselves against one of the best teams in the league, and to gain valuable experience before their relegation to the Championship.